hERG current

См. также в других словарях:

• HERG — The hERG (human Ether a go go Related Gene) (gene|KCNH2) encodes the Kv11.1 potassium ion channel responsible for the repolarizing IKr current in the cardiac action potential. tructureThe hERG potassium channel comprises 4 identical subunits each …   Wikipedia

• CCR5 receptor antagonists — are a class of small molecules that antagonize the CCR5 receptor. The C C motif chemokine receptor CCR5 is involved in the HIV entry process. Hence antagonists of this receptor have potential therapeutic applications in the treatment of HIV… …   Wikipedia

• Long QT syndrome — Infobox Disease Name = Long QT syndrome(Romano Ward syndrome) Caption = Schematic representation of normal ECG trace (sinus rhythm), with waves, segments, and intervals labeled. DiseasesDB = 11104 ICD10 = ICD10|I|45|8|i|30 ICD9 = ICD9|426.82 ICDO …   Wikipedia

• Azimilide — This is a class ΙΙΙ antiarrhythmic drug, which is used in treatment for rhythm control of the heart. The agents from this heterogeneous group have an effect on the repolarization, they prolongs the duration of the action potential and the… …   Wikipedia

• Voltage-gated potassium channel — Ion channel (eukariotic) Potassium channel, structure in a membrane like environment. Calculated hydrocarbon boundaries of the lipid bilayer are indicated by red and blue dots. Identifiers Symbol Ion trans …   Wikipedia

• Antitarget — In pharmacology, an antitarget is a receptor, enzyme, or other biological target that is affected by a drug, which causes undesirable side effects. During drug design and development, it is important for pharmaceutical companies to ensure that… …   Wikipedia

• Development of dipeptidyl peptidase-4 inhibitors — Dipeptidyl peptidase 4 inhibitors (DPP 4 inhibitors) are enzyme inhibitors that inhibit the enzyme dipeptidyl peptidase 4 (DPP 4) and are a potent treatment for type 2 diabetes. Inhibition of the DPP 4 enzyme prolongs and enhances the activity of …   Wikipedia

• KCNE2 — Potassium voltage gated channel, Isk related family, member 2 Identifiers Symbols KCNE2; ATFB4; LQT5; LQT6; MGC138292; MIRP1 External IDs …   Wikipedia

• Potassium channel — Top view of potassium ions (purple) moving through potassium channel (PDB 1BL8) In the field of cell biology, potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms …   Wikipedia

• Proteinfehlfaltungserkrankung — Als Proteinfehlfaltungserkrankungen, auch Proteinfaltungserkrankungen (engl. protein misfolding diseases oder protein misfolding disorders oder conformational diseases) genannt, bezeichnet man solche Erkrankungen, die durch falsche gefaltete… …   Deutsch Wikipedia

• KCNE1 — Potassium voltage gated channel, Isk related family, member 1, also known as KCNE1, is a human gene.cite web | title = Entrez Gene: KCNE1 potassium voltage gated channel, Isk related family, member 1| url =… …   Wikipedia